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DOI: 10.5530/ijper.56.3.108

Dose Conversion Between Animals and Humans: A Practical Solution(2022)

 

@Conversion by step

1. NOAEL determination

2. Scale NOAEL to HED

3. Select the more seneitive animal species

4. Divide by safety factor

5. PAD

 

@HED calcualtion based on BSA

 

@Dose conversion btw mg/kg to mg/m2

 

@Calculation of Km factor, Km Ratio, HED

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