Field Notes/Core Notes : ์‹ ์•ฝ๊ฐœ๋ฐœ
BCR-ABL kinase domain ๋Œ์—ฐ๋ณ€์ด์™€ imatinib ๋‚ด์„ฑ
2023.02.25
Reference: Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia (Cancer Cell, 2002) https://www.cell.com/cancer-cell/fulltext/S1535-6108(02)00096-X Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in..